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Capto adhere resin12/29/2023 ![]() Removal of leached Protein A, aggregates, host cell proteins, nucleic acids. As member of the BioProcess resins range, Capto adhere meets industrial demands with security of supply and comprehensive technical and regulatory support. Capto adhere is designed for post Protein A purification of monoclonal antibodies.Capto adhere is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development.For optimal performance of Capto adhere, screening/optimization of loading conditions is recommended, preferably using modern high-throughput process development tools, such as PreDictor 96-well filter plates. The results showed that the Capto family had the highest critical velocities (Capto Adhere- 492, Capto Q- 477 cm/hr), whilst Sepharose CL-6B, Sepharose 4 Fast. Product characteristics Capto adhere Capto adhere is composed of a rigid, high-flow agarose matrix and a multimodal ligand.a multimodal Capto adhere ImpRes AIEX medium was. Together with a Protein A capture step, like MabSelect SuRe, Capto adhere allows the design of a two-step chromatographic process for Mabs. modern chromatography media (resins) for standard as well as more challenging purification tasks.Capto adhere can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. The strong multimodal ligand gives a different selectivity compared to traditional ion exchangers.Composed of a rigid, high-flow agarose matrix and a novel multimodal ligand.Capto adhere is a multimodal BioProcess resin designed for post-protein A purification of monoclonal antibodies (MAbs) at process scale. A multimodal anion exchange resin designed for post-protein A purification of monoclonal antibodies at process scale. ![]()
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